People
Principal Investigator
Rachel A. Letteri
Assistant Professor
Department of Chemical Engineering
University of Virginia
rl2qm [at] virginia.edu
308 Wilsdorf Hall
B.S. Chemical and Biomolecular Engineering, University of Notre Dame, 2010, Research advisor: Paul Bohn
M.S. Polymer Science & Engineering, University of Massachusetts Amherst, 2012
Ph.D. Polymer Science & Engineering, University of Massachusetts Amherst, 2016, Thesis advisors: Todd Emrick and Ryan Hayward
Postdoctoral research: Department of Chemistry, Texas A&M University, Research Advisor: Karen Wooley
RAL Bio
Rachel A. Letteri is an Assistant Professor in the Department of Chemical Engineering at the University of Virginia. She obtained a B.S. in Chemical & Biomolecular Engineering from the University of Notre Dame in 2010 and a Ph.D. in Polymer Science & Engineering from the University of Massachusetts Amherst under the direction of Professors Todd Emrick and Ryan Hayward, prior to postdoctoral research in the laboratory of Professor Karen Wooley in the Department of Chemistry at Texas A&M University. Her research interests include polymer- and peptide-based materials with applications in medicine and engineering, and she is thrilled to be building a new lab with an outstanding group of researchers. Rachel thoroughly enjoys introducing second year undergraduates to chemical engineering through her Material & Energy Balances course. She also teaches Biochemical Engineering and a graduate course on Chemistry for Engineering Functional Soft Materials. In her free time, she enjoys cooking, running, and Notre Dame football.
Graduate Students
Mobina Alimadad
jhk2yh [at] virginia [dot] edu
B.S. Chemical Engineering, Sharif University of Technology, 2022
Ph.D. Student
Mobina is working on developing comb-shaped polymer-peptide conjugates with antimicrobial activities. Her research focuses on how the conjugates' peptide density and molecular weight affect their performance and stability. Outside of lab, Mobina enjoys cooking, watching movies, and discovering new places in the city.
Mark S. Bannon
msb6ph [at] virginia [dot] edu
B.S. Chemical Engineering, New Jersey Institute of Technology, 2017
M.S. Chemical Engineering, New Jersey Institute of Technology, 2018
M.S. Advisor: Kathleen McEnnis
Thesis: Interactions between Polymer Nanoparticles and Blood Plasma Applied to Drug Delivery Systems
UVA SEAS Dean's Scholar
2021 Dupont Safety Awardee
Ph.D. Candidate
Mark's research focuses on developing drug delivery strategies for therapeutic peptides to increase their in vivo stability. Specifically, Mark uses exosomes, polyelectrolyte complexes and polymer-metal organic framework hydrogels to encapsulate therapeutic peptide cargo. Outside of lab, Mark enjoys playing guitar and coaching boys lacrosse for Albemarle High School.
Kelly M. Bukovic
kmb5pu [at] virginia [dot] edu
B.S. Chemical Engineering, University of Florida, 2020
UVA SEAS Dean's Scholar
Jointly advised by Steven Caliari
Kelly is interested in developing novel cell culture systems for the advancement of tissue engineering and regenerative medicine. Specifically, she studies cellular responses to thermoresponsive polymeric culture substrates for biomanufacturing engineered skeletal muscle tissue. When not in lab, Kelly enjoys gardening, visiting wineries and art museums, crocheting, and barre.
Zixian Cui
zc6pa [at] virginia [dot] edu
B.E. Chemical Engineering, East China University of Science and Technology, 2016
M.S. Chemical Engineering, Carnegie Mellon University 2017
2020 Gaden Awardee
Ph.D. Candidate
Zixian is working on antimicrobial peptide-polymer conjugates to improve the proteolytic stability and reduce cytotoxicity while maintaining antibacterial activity of the peptides. She is interested in engineering the molecular structures (e.g., linear, star-shaped, comb-like, and hyperbranched) of the conjugates to study the architectural effects on activity, stability, and toxicity. Zixian is working with Chris to study the kinetics of polymerization to prepare comb-like conjugates. Outside of lab, she loves movies, music, and literature.
Israt Jahan Duti
id8nu [at] virginia [dot] edu
B.S. Chemical Engineering, Bangladesh University of Engineering and Technology, 2016
M.S. Chemical Engineering, Bangladesh University of Engineering and Technology, 2018
Ph.D. Candidate
Israt is developing hydrogels with controllable thermomechanical properties and proteolytic degradability. In particular, she works on designing peptide stereocomplexes as dynamic cross-linkers in polymeric hydrogels. In her free time, she enjoys movies, painting, and crafting.
Aditi Gourishankar
jkd4kk [at] virginia [dot] edu
Ph.D. Student
Jerwin C. Lawrence Go
ruy6bd [at] virginia [dot] edu
2022 Gaden Awardee
Ph.D. Student
Vincent P. Gray
vg9cm [at] virginia [dot] edu
B.E. Chemical Engineering, Youngstown State University, 2018
UVA SEAS Dean's Scholar
UVA Distinguished Fellow
NIH Biotechnology Training Program Fellow
Ph.D. Candidate
Vince is designing biomaterials to target and sequester toxic peptides implicated in amyotrophic lateral sclerosis using stereochemistry-driven and electrostatic interactions. Specifically, he uses characterization techniques to explore the interactions between peptides and optimize the design of biomaterials. Outside of lab, Vince enjoys playing disc golf and ultimate frisbee, hiking, listening to music, and reading.
Darren Miller
htr7ww [at] virginia [dot] edu
B.S. Chemical Engineering 2017
W.L. Gore & Assoc. 2017-2022
Ph.D. Student
Darren's research focuses on designing hydrogels with controllable mechanical properties and proteolytic degradability. Specifically, he is investigating peptide stereochemical-directed interactions to help establish design rules for using these molecules as dynamic cross-linkers in polymeric hydrogels. Outside of lab, Darren enjoys cooking, golf, and hiking.
Hadley Mosby
fwh9gq [at] virginia.edu
B.S. Chemical Engineering, University of Iowa, 2023
Ph.D. Student
Hadley is working on designing D-peptides to capture L-peptides for therapeutic separation applications. More specifically, she is investigating the stereochemistry-driven interactions that occur between D- and L- peptides, and how they can be applied to separations. Outside of lab, Hadley enjoys reading, cooking, going for walks, and trying new coffee shops.
Undergraduate Students
Joshua Alexander
yax8zn [at] virginia [dot] edu
UVA Biomedical Engineering Class of 2024
Elli Brna
jtv5cs [at] virginia [dot] edu
UVA Chemical Engineering Class of 2025
Clare Cocker
cec5fc [at] virginia [dot] edu
UVA Chemical Engineering Class of 2024
Jointly advised by Kyle Lampe and Phillip Taylor
Clare conducts experiments and molecular dynamic simulations to understand stereochemically-driven assembly of peptides. Around SEAS she also is a mentor in SURE (Starting and Undergraduate Research Experience) and a member of Theta Tau. For fun she enjoys trying new crafts and hiking.
Jack Dunleavy
jcd2evu [at] virginia [dot] edu
UVA Chemical Engineering Class of 2024
Jack's research focuses on the analysis of various methods for encapsulation and controlled release of therapeutic peptide cargo. Outside of the lab, Jack enjoys skateboarding, yoga, and art.
Mackenzie Klepsig
gjm8rk [at] virginia [dot] edu
UVA Chemical Engineering Class of 2025
Keelin Reilly
ptk8gg [at] virginia.edu
UVA Biomedical Engineering Class of 2025
Alumni
Postdocs
Dr. Qinmo Luo, 2020-2021, currently at Merck
PhDs
Dr. Mara Kuenen, 2018-2023, currently a postdoctoral research associate at the University of Minnesota in Marc Hillmyer's lab
Undergraduates
Jonathan Paul, 2021-2023, currently a Ph.D. student in chemical engineering at the University of Colorado Boulder
Chris Hawkins, 2021-2022, currently at NREL
Justin Harrington, 2021-2022, currently a Ph.D. student in chemical engineering at the University of Delaware
Taylor Bloom, 2020-2022, currently an M.S. in Biopharmaceutical Sciences student at the University of Delaware
Alexa Cuomo, Summer 2021
James Mullin, 2018-2021, currently a Ph.D. student in chemical engineering at the University of Delaware in Millie Sullivan's lab
Emma Laudermilch, 2018-2021, currently a process development engineer at Illumina in San Diego, CA
Justin Fernandes, 2019-2020
Jessie Eoff, 2018-2020
Madeline Clore, 2018-2020, currently teaching math at The Calverton School in Huntingtown, MD
Becca Richardson, 2018-2020, currently a patent examiner at the US Patent and Trademark Office in Alexandria, VA and attending George Washington Law School
Elyse He'Bert, Summer 2019